8HN8

Cryo-EM structure of ligand histamine-bound Histamine H4 receptor Gi complex

8HN8 の概要

• エントリーDOI: 10.2210/pdb8hn8/pdb
• EMDBエントリー: 34908
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: gpcr complex, agonist, histamine receptor, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 180427.15

構造登録者

Tang, W.Q.,Sun, X.Y.,Li, F.H.,Wang, J.Y. (登録日: 2022-12-07, 公開日: 2023-12-20)

• 主引用文献: Sun, X.Y.,Li, F.H.,Wang, J.Y.; Structure insights into Histamine H4 receptor activation by an endogenous ligand histamine and agonist imetit; To Be Published,

実験手法

ELECTRON MICROSCOPY (3 Å)