8HLA

Heteromeric ring comprised of peroxiredoxin from Thermococcus kodakaraensis (TkPrx) F42C/C46S/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F42C) and TkPrx C46S/F76C/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F76C) (Naph@(MIX|3:3))

Summary for 8HLA

• Entry DOI: 10.2210/pdb8hla/pdb
• Related: 8HH0
• EMDB information: 34859
• Descriptor: Peroxiredoxin, 1-naphthalen-2-ylethanone (3 entities in total)
• Functional Keywords: peroxiredoxin, complex, protein protein interactions, oxidoreductase
• Biological source: Thermococcus kodakarensis KOD1; More
• Total number of polymer chains: 12
• Total formula weight: 297064.19

Authors

Himiyama, T.,Hamaguchi, T.,Yonekura, K.,Nakamura, T. (deposition date: 2022-11-29, release date: 2023-03-22, Last modification date: 2023-12-13)

• Primary citation: Himiyama, T.,Hamaguchi, T.,Yonekura, K.,Nakamura, T.; Unnaturally Distorted Hexagonal Protein Ring Alternatingly Reorganized from Two Distinct Chemically Modified Proteins.; Bioconjug.Chem., 2023; PubMed: 36888722; DOI: 10.1021/acs.bioconjchem.3c00057

Experimental method

ELECTRON MICROSCOPY (2.81 Å)