8HL6

Crystal structure of human valosin-containing protein methyltransferase

Summary for 8HL6

Entry DOI	10.2210/pdb8hl6/pdb
Descriptor	Protein N-lysine methyltransferase METTL21D, S-ADENOSYLMETHIONINE (3 entities in total)
Functional Keywords	vcpkmt, methyltransferase, aspl, aspscr1, ubxd9, tug, protein binding
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	27063.92
Authors	Kang, W.,Yang, J.K. (deposition date: 2022-11-29, release date: 2023-07-12, Last modification date: 2024-05-29)
Primary citation	Nguyen, T.Q.,Koh, S.,Kwon, J.,Jang, S.,Kang, W.,Yang, J.K. Structural basis for recognition and methylation of p97 by METTL21D, a valosin-containing protein lysine methyltransferase. Iscience, 26:107222-107222, 2023 Cited by PubMed: 37456834 DOI: 10.1016/j.isci.2023.107222 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation