8HFJ
Crystal Structure of CbAR mutant (H162F) in complex with NADP+ and a bulky 1,3-cyclodiketone
Summary for 8HFJ
Entry DOI | 10.2210/pdb8hfj/pdb |
Descriptor | Versicolorin reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-methyl-2-[(4-methylphenyl)methyl]cyclopentane-1,3-dione, ... (4 entities in total) |
Functional Keywords | anthrol reductase, chiral alcohol, emodin, oxidoreductase |
Biological source | Cercospora sp. JNU001 |
Total number of polymer chains | 4 |
Total formula weight | 123905.93 |
Authors | |
Primary citation | Hou, X.,Xu, H.,Yuan, Z.,Deng, Z.,Fu, K.,Gao, Y.,Liu, C.,Zhang, Y.,Rao, Y. Structural analysis of an anthrol reductase inspires enantioselective synthesis of enantiopure hydroxycycloketones and beta-halohydrins. Nat Commun, 14:353-353, 2023 Cited by PubMed: 36681664DOI: 10.1038/s41467-023-36064-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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