8HD3

Farnesoid X Receptor Agonists_FXR fused with a HD3 peptide

Summary for 8HD3

• Entry DOI: 10.2210/pdb8hd3/pdb
• Descriptor: Farnesoid X Receptor, [(3s,5s,7s)-adamantan-1-yl][4-(2-amino-5-chlorophenyl)piperazin-1-yl]methanone (3 entities in total)
• Functional Keywords: bile acid receptor, agonist, farnesoid x-activated receptor, nuclear protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 60684.30

Authors

Lu, X.,Zhang, H. (deposition date: 2022-11-03, release date: 2023-11-08)

• Primary citation: Lu, X.,Zhang, H.; Crystal structure of FXR fused with a HD3 peptide in complex with agonist QT0127; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.29 Å)