8HCA

SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 3 YB13-292 Fabs (1 RBD up)

Summary for 8HCA

• Entry DOI: 10.2210/pdb8hca/pdb
• EMDB information: 34657
• Descriptor: Spike glycoprotein, Light chain of YB13-292 Fab, Heavy chain of YB13-292 Fab, ... (5 entities in total)
• Functional Keywords: spike protein, rbd, antibody, fab, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 9
• Total formula weight: 573617.75

Authors

Liu, B.,Gao, X.,Chen, Q.,Li, Z.,Su, M.,He, J.,Xiong, X. (deposition date: 2022-11-01, release date: 2023-01-25, Last modification date: 2023-05-03)

• Primary citation: Yu, H.,Liu, B.,Zhang, Y.,Gao, X.,Wang, Q.,Xiang, H.,Peng, X.,Xie, C.,Wang, Y.,Hu, P.,Shi, J.,Shi, Q.,Zheng, P.,Feng, C.,Tang, G.,Liu, X.,Guo, L.,Lin, X.,Li, J.,Liu, C.,Huang, Y.,Yang, N.,Chen, Q.,Li, Z.,Su, M.,Yan, Q.,Pei, R.,Chen, X.,Liu, L.,Hu, F.,Liang, D.,Ke, B.,Ke, C.,Li, F.,He, J.,Wang, M.,Chen, L.,Xiong, X.,Tang, X.; Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants.; Nat Commun, 14:1058-1058, 2023; PubMed: 36828833; DOI: 10.1038/s41467-023-36761-0

Experimental method

ELECTRON MICROSCOPY (4.35 Å)