8HB0
Structure of human SGLT2-MAP17 complex with TA1887
Summary for 8HB0
Entry DOI | 10.2210/pdb8hb0/pdb |
EMDB information | 34610 |
Descriptor | Sodium/glucose cotransporter 2, PDZK1-interacting protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | ion transport, sodium transport, sugar transport, symport, transport protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 86154.37 |
Authors | Hiraizumi, M.,Kishida, H.,Miyaguchi, I.,Nureki, O. (deposition date: 2022-10-27, release date: 2023-11-01, Last modification date: 2024-02-07) |
Primary citation | Hiraizumi, M.,Akashi, T.,Murasaki, K.,Kishida, H.,Kumanomidou, T.,Torimoto, N.,Nureki, O.,Miyaguchi, I. Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter. Nat.Struct.Mol.Biol., 31:159-169, 2024 Cited by PubMed: 38057552DOI: 10.1038/s41594-023-01134-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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