8HAO

Human parathyroid hormone receptor-1 dimer

8HAO の概要

• エントリーDOI: 10.2210/pdb8hao/pdb
• EMDBエントリー: 34585 34587 34598
• 分子名称: Guanine nucleotide-binding protein G(s) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: pth1r, gpcr, lipid binding protein-hormone-immune system complex, lipid binding protein/hormone/immune system
• 由来する生物種: Bos taurus (cattle); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 334841.79

構造登録者

Zhao, L.,Xu, H.E.,Yuan, Q. (登録日: 2022-10-26, 公開日: 2022-12-21, 最終更新日: 2023-05-31)

• 主引用文献: Zhao, L.H.,Yuan, Q.N.,Dai, A.T.,He, X.H.,Chen, C.W.,Zhang, C.,Xu, Y.W.,Zhou, Y.,Wang, M.W.,Yang, D.H.,Xu, H.E.; Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1.; Acta Pharmacol.Sin., 44:1227-1237, 2023; PubMed: 36482086; DOI: 10.1038/s41401-022-01032-z

実験手法

ELECTRON MICROSCOPY (3.76 Å)