8H4I

DHA-bound FFAR4 in complex with Gs

Summary for 8H4I

• Entry DOI: 10.2210/pdb8h4i/pdb
• EMDB information: 34478 34479 34480
• Descriptor: engineered mini Galpha-S subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: gpcr-g-protein complex, membrane protein-immune system complex, membrane protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 145899.39

Authors

He, Y.,Yin, H. (deposition date: 2022-10-10, release date: 2023-06-21, Last modification date: 2024-11-20)

• Primary citation: Yin, H.,Inoue, A.,Ma, Z.,Zhu, X.,Xia, R.,Xu, Z.,Wang, N.,Duan, Y.,Zhang, A.,Guo, C.,He, Y.; Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity.; Cell Res., 33:644-647, 2023; PubMed: 37286793; DOI: 10.1038/s41422-023-00835-x

Experimental method

ELECTRON MICROSCOPY (3.06 Å)