8H34
Cryo-EM Structure of the KBTBD2-Cul3-Rbx1 hexameric complex
Summary for 8H34
Entry DOI | 10.2210/pdb8h34/pdb |
EMDB information | 34450 |
Descriptor | Cullin-3, Kelch repeat and BTB domain-containing protein 2, E3 ubiquitin-protein ligase RBX1, ... (4 entities in total) |
Functional Keywords | ligase, complex |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 18 |
Total formula weight | 1047802.07 |
Authors | |
Primary citation | Hu, Y.,Zhang, Z.,Mao, Q.,Zhang, X.,Hao, A.,Xun, Y.,Wang, Y.,Han, L.,Zhan, W.,Liu, Q.,Yin, Y.,Peng, C.,Moresco, E.M.Y.,Chen, Z.,Beutler, B.,Sun, L. Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2. Nat.Struct.Mol.Biol., 31:336-350, 2024 Cited by PubMed: 38332366DOI: 10.1038/s41594-023-01182-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (7.99 Å) |
Structure validation
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