8H2G

Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer

8H2G の概要

• エントリーDOI: 10.2210/pdb8h2g/pdb
• EMDBエントリー: 34437
• 分子名称: Hydroxy-carboxylic acid receptor 2, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
• 機能のキーワード: gpcr, hydroxycarboxylic acid, g-protein, membrane protein, niacin, signaling
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 168502.94

構造登録者

Park, J.H.,Ishimoto, N.,Park, S.Y. (登録日: 2022-10-06, 公開日: 2023-10-11)

• 主引用文献: Park, J.H.,Ishimoto, N.,Kawakami, K.,Ikuta, T.,Ohki, M.,Ekimoto, T.,Ikeguchi, M.,Lee, D.S.,Lee, Y.H.,Tame, J.R.H.,Inoue, A.,Park, S.Y.; Structural basis for hydroxy-carboxylic acid receptor 2 activation and allosteric mechanism; To Be Published,

実験手法

ELECTRON MICROSCOPY (3.01 Å)