8GZ6
Crystal structure of neutralizing VHH P17 in complex with SARS-CoV-2 Alpha variant spike receptor-binding domain
Summary for 8GZ6
Entry DOI | 10.2210/pdb8gz6/pdb |
Related | 8GZ5 |
Descriptor | Nanobody P17, CHLORIDE ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | sars-cov-2, spike rbd, nanobody, vhh, viral protein, immune system |
Biological source | Vicugna pacos |
Total number of polymer chains | 2 |
Total formula weight | 27351.96 |
Authors | Yamaguchi, K.,Anzai, I.,Maeda, R.,Moriguchi, M.,Watanabe, T.,Imura, A.,Takaori-Kondo, A.,Inoue, T. (deposition date: 2022-09-25, release date: 2022-12-07, Last modification date: 2023-11-29) |
Primary citation | Yamaguchi, K.,Anzai, I.,Maeda, R.,Moriguchi, M.,Watanabe, T.,Imura, A.,Takaori-Kondo, A.,Inoue, T. Structural insights into the rational design of a nanobody that binds with high affinity to the SARS-CoV-2 spike variant. J.Biochem., 173:115-127, 2023 Cited by PubMed: 36413757DOI: 10.1093/jb/mvac096 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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