8GUY
human insulin receptor bound with two insulin molecules
Summary for 8GUY
Entry DOI | 10.2210/pdb8guy/pdb |
EMDB information | 34281 |
Descriptor | Isoform Short of Insulin receptor, Insulin A chain, Insulin, isoform 2 (3 entities in total) |
Functional Keywords | receptor-ligand complex, structural protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 217735.05 |
Authors | |
Primary citation | Kim, J.,Yunn, N.O.,Park, M.,Kim, J.,Park, S.,Kim, Y.,Noh, J.,Ryu, S.H.,Cho, Y. Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures. Nat Commun, 13:6500-6500, 2022 Cited by PubMed: 36310231DOI: 10.1038/s41467-022-34292-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.18 Å) |
Structure validation
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