8GT4
Crystal structure of human cardiac alpha actin Q137A mutant (AMPPNP state) in complex with fragmin F1 domain
Summary for 8GT4
Entry DOI | 10.2210/pdb8gt4/pdb |
Descriptor | Actin, alpha cardiac muscle 1, Actin-binding protein fragmin P, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (8 entities in total) |
Functional Keywords | actin dynamics, atp hydrolysis, mutagenesis, md simulation, contractile protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 62611.52 |
Authors | Iwasa, M.,Oda, T.,Takeda, S. (deposition date: 2022-09-07, release date: 2023-03-08, Last modification date: 2023-11-29) |
Primary citation | Iwasa, M.,Takeda, S.,Narita, A.,Maeda, Y.,Oda, T. Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11:1105460-1105460, 2023 Cited by PubMed: 37009486DOI: 10.3389/fcell.2023.1105460 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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