8GQ5
Human SARM1 bounded with NMN and Nanobody-C6, double-layer structure
Summary for 8GQ5
Entry DOI | 10.2210/pdb8gq5/pdb |
EMDB information | 34198 |
Descriptor | NAD(+) hydrolase SARM1, Nanobody C6 (2 entities in total) |
Functional Keywords | nad(+)hydrolase, nmn, nanobody, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 32 |
Total formula weight | 1482478.69 |
Authors | |
Primary citation | Hou, Y.N.,Cai, Y.,Li, W.H.,He, W.M.,Zhao, Z.Y.,Zhu, W.J.,Wang, Q.,Mai, X.,Liu, J.,Lee, H.C.,Stjepanovic, G.,Zhang, H.,Zhao, Y.J. A conformation-specific nanobody targeting the nicotinamide mononucleotide-activated state of SARM1. Nat Commun, 13:7898-7898, 2022 Cited by PubMed: 36550129DOI: 10.1038/s41467-022-35581-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
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