8GMR
Cryo-EM structure of octameric human CALHM1
Summary for 8GMR
| Entry DOI | 10.2210/pdb8gmr/pdb |
| EMDB information | 40231 |
| Descriptor | Calcium homeostasis modulator protein 1, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (2 entities in total) |
| Functional Keywords | taste, assembly, calcium homeostasis modulator protein, membrane protein, channel, lipid binding, large-pore channel |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 8 |
| Total formula weight | 284236.48 |
| Authors | Syrjanen, J.L.,Furukawa, H. (deposition date: 2023-03-27, release date: 2023-07-26, Last modification date: 2024-05-01) |
| Primary citation | Syrjanen, J.L.,Epstein, M.,Gomez, R.,Furukawa, H. Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red. Nat Commun, 14:3821-3821, 2023 Cited by PubMed: 37380652DOI: 10.1038/s41467-023-39388-3 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.76 Å) |
Structure validation
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