8GLS

Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and Z1834339853

Summary for 8GLS

• Entry DOI: 10.2210/pdb8gls/pdb
• EMDB information: 40207
• Descriptor: Cystic fibrosis transmembrane conductance regulator, human cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: transporter, ion channel, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 174975.94

Authors

Liu, F.,Chen, J. (deposition date: 2023-03-23, release date: 2024-06-26)

• Primary citation: Liu, F.,Kaplan, A.L.,Levring, J.,Einsiedel, J.,Tiedt, S.,Distler, K.,Omattage, N.S.,Kondratov, I.S.,Moroz, Y.S.,Irwin, J.J.,Gmeiner, P.,Shoichet, B.K.,Chen, J.; Structure-based discovery of positive and negative CFTR modulators; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.8 Å)