8GFY

CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #4 of 20)

Summary for 8GFY

Entry DOI	10.2210/pdb8gfy/pdb
EMDB information	29988
Descriptor	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
Functional Keywords	gpcr, adrenergic, receptor, g protein, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	142260.95
Authors	Papasergi-Scott, M.M.,Skiniotis, G. (deposition date: 2023-03-08, release date: 2024-03-06, Last modification date: 2024-03-27)
Primary citation	Papasergi-Scott, M.M.,Perez-Hernandez, G.,Batebi, H.,Gao, Y.,Eskici, G.,Seven, A.B.,Panova, O.,Hilger, D.,Casiraghi, M.,He, F.,Maul, L.,Gmeiner, P.,Kobilka, B.K.,Hildebrand, P.W.,Skiniotis, G. Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 2024 Cited by PubMed: 38480881 DOI: 10.1038/s41586-024-07153-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation