8GB4

EGFR(T790M/V948R) kinase in complex with benzimidazole allosteric inhibitor

Summary for 8GB4

• Entry DOI: 10.2210/pdb8gb4/pdb
• Descriptor: Epidermal growth factor receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
• Functional Keywords: egfr, kinase, allosteric, inhibitor, cancer, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 155142.94

Authors

Beyett, T.S.,Eck, M.J. (deposition date: 2023-02-24, release date: 2024-03-13)

• Primary citation: Beyett, T.S.,Eck, M.J.; EGFR(T790M/V948R) kinase in complex with benzimidazole allosteric inhibitor; To be published,

Experimental method

X-RAY DIFFRACTION (2.59 Å)