8G8W
Molecular mechanism of nucleotide inhibition of human uncoupling protein 1
Summary for 8G8W
Entry DOI | 10.2210/pdb8g8w/pdb |
EMDB information | 29857 |
Descriptor | Mitochondrial brown fat uncoupling protein 1, Pro-macrobody 71, Maltose/maltodextrin-binding periplasmic protein chimera, Pro-Macrobody 65, Maltose/maltodextrin-binding periplasmic protein chimera, ... (6 entities in total) |
Functional Keywords | slc25, mitochondrial carrier, uncoupling, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 146103.96 |
Authors | Gogoi, P.,Jones, S.A.,Ruprecht, J.J.,King, M.S.,Lee, Y.,Zogg, T.,Pardon, E.,Chand, D.,Steimle, S.,Copeman, D.,Cotrim, C.A.,Steyaert, J.,Crichton, P.G.,Moiseenkova-Bell, V.,Kunji, E.R.S. (deposition date: 2023-02-20, release date: 2023-06-07) |
Primary citation | Jones, S.A.,Gogoi, P.,Ruprecht, J.J.,King, M.S.,Lee, Y.,Zogg, T.,Pardon, E.,Chand, D.,Steimle, S.,Copeman, D.M.,Cotrim, C.A.,Steyaert, J.,Crichton, P.G.,Moiseenkova-Bell, V.,Kunji, E.R.S. Structural basis of purine nucleotide inhibition of human uncoupling protein 1. Sci Adv, 9:eadh4251-eadh4251, 2023 Cited by PubMed: 37256948DOI: 10.1126/sciadv.adh4251 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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