8G8W

Molecular mechanism of nucleotide inhibition of human uncoupling protein 1

8G8W の概要

• エントリーDOI: 10.2210/pdb8g8w/pdb
• EMDBエントリー: 29857
• 分子名称: Mitochondrial brown fat uncoupling protein 1, Pro-macrobody 71, Maltose/maltodextrin-binding periplasmic protein chimera, Pro-Macrobody 65, Maltose/maltodextrin-binding periplasmic protein chimera, ... (6 entities in total)
• 機能のキーワード: slc25, mitochondrial carrier, uncoupling, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 146103.96

構造登録者

Gogoi, P.,Jones, S.A.,Ruprecht, J.J.,King, M.S.,Lee, Y.,Zogg, T.,Pardon, E.,Chand, D.,Steimle, S.,Copeman, D.,Cotrim, C.A.,Steyaert, J.,Crichton, P.G.,Moiseenkova-Bell, V.,Kunji, E.R.S. (登録日: 2023-02-20, 公開日: 2023-06-07)

• 主引用文献: Jones, S.A.,Gogoi, P.,Ruprecht, J.J.,King, M.S.,Lee, Y.,Zogg, T.,Pardon, E.,Chand, D.,Steimle, S.,Copeman, D.M.,Cotrim, C.A.,Steyaert, J.,Crichton, P.G.,Moiseenkova-Bell, V.,Kunji, E.R.S.; Structural basis of purine nucleotide inhibition of human uncoupling protein 1.; Sci Adv, 9:eadh4251-eadh4251, 2023; PubMed: 37256948; DOI: 10.1126/sciadv.adh4251

実験手法

ELECTRON MICROSCOPY (3.8 Å)