8G4Z

E. coli DHFR complex with NADP+ and folate: EF-X off model by Laue diffraction (no electric field)

Summary for 8G4Z

Entry DOI	10.2210/pdb8g4z/pdb
Descriptor	Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
Functional Keywords	dihydrofolate reductase, oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	19510.83
Authors	Greisman, J.B.,Dalton, K.M.,Brookner, D.E.,Klureza, M.A.,Hekstra, D.R. (deposition date: 2023-02-10, release date: 2024-01-03, Last modification date: 2024-07-24)
Primary citation	Greisman, J.B.,Dalton, K.M.,Brookner, D.E.,Klureza, M.A.,Sheehan, C.J.,Kim, I.S.,Henning, R.W.,Russi, S.,Hekstra, D.R. Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121:e2313192121-e2313192121, 2024 Cited by PubMed: 38386706 DOI: 10.1073/pnas.2313192121 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation