8G4X

Native GABA-A receptor from the mouse brain, meta-alpha1-alpha3-beta2-gamma2 subtype, in complex with GABA and allopregnanolone

これはPDB形式変換不可エントリーです。

8G4X の概要

• エントリーDOI: 10.2210/pdb8g4x/pdb
• EMDBエントリー: 29733
• 分子名称: Gamma-aminobutyric acid receptor subunit alpha-1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (15 entities in total)
• 機能のキーワード: ligand-gated ion channel, cys-loop receptor, neurotransmitter receptor, membrane protein
• 由来する生物種: Mus musculus; 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 337023.84

構造登録者

Sun, C.,Gouaux, E. (登録日: 2023-02-10, 公開日: 2023-09-20, 最終更新日: 2023-11-15)

• 主引用文献: Sun, C.,Zhu, H.,Clark, S.,Gouaux, E.; Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology.; Nature, 622:195-201, 2023; PubMed: 37730991; DOI: 10.1038/s41586-023-06556-w

実験手法

ELECTRON MICROSCOPY (2.56 Å)