8G4V

Horse liver alcohol dehydrogense His-51-Gln form complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol

Summary for 8G4V

• Entry DOI: 10.2210/pdb8g4v/pdb
• Related: 1qv6 1qv7 4dwv 8g2l 8g2s 8g39
• Descriptor: Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total)
• Functional Keywords: alcohol dehydrogenase horse liver his-51- gln substitution, complex with nad+ and pentafluorobenzyl alcohol, oxidoreductase
• Biological source: Equus caballus (horse)
• Total number of polymer chains: 2
• Total formula weight: 81789.36

Authors

Plapp, B.V.,Subramanian, R. (deposition date: 2023-02-10, release date: 2023-02-22, Last modification date: 2024-09-04)

• Primary citation: Plapp, B.V.,Kovaleva, E.G.; Histidine-51 facilitates deprotonation of the zinc-bound ligand during catalysis by horse liver alcohol dehydrogenase; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.2 Å)