8G4P

Crystal structure of the peanut allergen Ara h 2 bound by two neutralizing antibodies 13T1 and 13T5

Summary for 8G4P

• Entry DOI: 10.2210/pdb8g4p/pdb
• Descriptor: 13t1 Fab heavy chain, 13T1 Fab light chain, 13T5 Fab heavy chain, ... (10 entities in total)
• Functional Keywords: allergy, antibody, peanut, epitope, paratope, allergen
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 113682.09

Authors

Pedersen, L.C.,Mueller, G.A.,Min, J. (deposition date: 2023-02-10, release date: 2023-12-20, Last modification date: 2024-01-31)

• Primary citation: Min, J.,Keswani, T.,LaHood, N.A.,Lytle, I.R.,Marini-Rapoport, O.,Andrieux, L.,Sneed, S.L.,Edwards, L.L.,Petrovich, R.M.,Perera, L.,Pomes, A.,Pedersen, L.C.,Patil, S.U.,Mueller, G.A.; Design of an Ara h 2 hypoallergen from conformational epitopes.; Clin Exp Allergy, 54:46-55, 2024; PubMed: 38168500; DOI: 10.1111/cea.14433

Experimental method

X-RAY DIFFRACTION (2.25 Å)