8G2Y
Cryo-EM structure of ADGRF1 coupled to miniGs/q
Summary for 8G2Y
Entry DOI | 10.2210/pdb8g2y/pdb |
EMDB information | 29684 |
Descriptor | MiniG alpha s/q chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | gpcr, agonist, g protein, signaling, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 161147.44 |
Authors | |
Primary citation | Jones, D.T.D.,Dates, A.N.,Rawson, S.D.,Burruss, M.M.,Lipper, C.H.,Blacklow, S.C. Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling. Nat Commun, 14:2490-2490, 2023 Cited by PubMed: 37120430DOI: 10.1038/s41467-023-38083-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.44 Å) |
Structure validation
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