8G2V

Cryo-EM structure of recombinant human LECT2 amyloid fibril core

Summary for 8G2V

Entry DOI	10.2210/pdb8g2v/pdb
EMDB information	29682
Descriptor	Leukocyte cell-derived chemotaxin-2 (1 entity in total)
Functional Keywords	amyloid, lect2, human, recombinant, fibril, protein, alect2, cryo-em, protein fibril
Biological source	Homo sapiens (human)
Total number of polymer chains	10
Total formula weight	23897.52
Authors	Richards, L.S.,Flores, M.D.,Zink, S.,Schibrowsky, N.A.,Sawaya, M.R.,Rodriguez, J.A. (deposition date: 2023-02-06, release date: 2023-08-16, Last modification date: 2023-11-15)
Primary citation	Richards, L.S.,Flores, M.D.,Zink, S.,Schibrowsky, N.A.,Sawaya, M.R.,Rodriguez, J.A. Cryo-EM structure of a human LECT2 amyloid fibril reveals a network of polar ladders at its core. Structure, 31:1386-1393.e3, 2023 Cited by PubMed: 37657439 DOI: 10.1016/j.str.2023.08.007 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.715 Å)

Structure validation