8FZQ
Dehosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR)
Summary for 8FZQ
Entry DOI | 10.2210/pdb8fzq/pdb |
EMDB information | 29637 |
Descriptor | Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total) |
Functional Keywords | ion channel, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 169922.03 |
Authors | Levring, J.,Terry, D.S.,Kilic, Z.,Fitzgerald, G.A.,Blanchard, S.C.,Chen, J. (deposition date: 2023-01-29, release date: 2023-03-29, Last modification date: 2024-06-19) |
Primary citation | Levring, J.,Terry, D.S.,Kilic, Z.,Fitzgerald, G.,Blanchard, S.,Chen, J. CFTR function, pathology and pharmacology at single-molecule resolution. Nature, 616:606-614, 2023 Cited by PubMed: 36949202DOI: 10.1038/s41586-023-05854-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.3 Å) |
Structure validation
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