8FSJ
Cryo-EM structure of engineered hepatitis C virus E1E2 ectodomain in complex with antibodies AR4A, HEPC74, and IGH520
Summary for 8FSJ
Entry DOI | 10.2210/pdb8fsj/pdb |
EMDB information | 29419 |
Descriptor | HCV E2 ectodomain, SYNZIP2 scaffold fusion, HEPC74 heavy chain, HEPC74 light chain, ... (9 entities in total) |
Functional Keywords | hcv, e1e2, viral protein |
Biological source | Hepacivirus C More |
Total number of polymer chains | 6 |
Total formula weight | 180343.45 |
Authors | |
Primary citation | Metcalf, M.C.,Janus, B.M.,Yin, R.,Wang, R.,Guest, J.D.,Pozharski, E.,Law, M.,Mariuzza, R.A.,Toth, E.A.,Pierce, B.G.,Fuerst, T.R.,Ofek, G. Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies. Nat Commun, 14:3980-3980, 2023 Cited by PubMed: 37407593DOI: 10.1038/s41467-023-39659-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.65 Å) |
Structure validation
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