8FSI

The structure of a crystallizable variant of E. coli pyruvate formate-lyase activating enzyme bound to SAM

8FSI の概要

• エントリーDOI: 10.2210/pdb8fsi/pdb
• 関連するPDBエントリー: 8FO0 8FOL
• 分子名称: Pyruvate formate-lyase 1-activating enzyme, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ... (6 entities in total)
• 機能のキーワード: radical sam, activase, pfl, oxidoreductase
• 由来する生物種: Escherichia coli K-12
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29101.00

構造登録者

Moody, J.D.,Galambas, A.,Lawrence, C.M.,Broderick, J.B. (登録日: 2023-01-10, 公開日: 2023-05-24, 最終更新日: 2023-06-21)

• 主引用文献: Moody, J.D.,Hill, S.,Lundahl, M.N.,Saxton, A.J.,Galambas, A.,Broderick, W.E.,Lawrence, C.M.,Broderick, J.B.; Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage.; J.Biol.Chem., 299:104791-104791, 2023; PubMed: 37156396; DOI: 10.1016/j.jbc.2023.104791

実験手法

X-RAY DIFFRACTION (1.46 Å)