8FRT
X-ray crystal structure of the N-terminal region from HCMV US11 binding to HLA-A*02:01
Summary for 8FRT
Entry DOI | 10.2210/pdb8frt/pdb |
Descriptor | Unique short US11 glycoprotein, Beta-2-microglobulin, MHC class I HLA-A fusion, GLYCEROL (3 entities in total) |
Functional Keywords | immunoevasin, molecular mimicry, immune system |
Biological source | Human cytomegalovirus (strain AD169) (HHV-5) More |
Total number of polymer chains | 1 |
Total formula weight | 49748.74 |
Authors | |
Primary citation | Zimmermann, C.,Watson, G.M.,Bauersfeld, L.,Berry, R.,Ciblis, B.,Lan, H.,Gerke, C.,Oberhardt, V.,Fuchs, J.,Hofmann, M.,Freund, C.,Rossjohn, J.,Momburg, F.,Hengel, H.,Halenius, A. Diverse cytomegalovirus US11 antagonism and MHC-A evasion strategies reveal a tit-for-tat coevolutionary arms race in hominids. Proc.Natl.Acad.Sci.USA, 121:e2315985121-e2315985121, 2024 Cited by PubMed: 38377192DOI: 10.1073/pnas.2315985121 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report