8FPA

Structure of a chimeric antibody (Fab) fragment bound to de-N-acetyl polysialic acid (dPSA)

Summary for 8FPA

• Entry DOI: 10.2210/pdb8fpa/pdb
• Descriptor: Chimeric antibody Fab fragment, Fd chain, Humanized antibody Fab fragment, light chain, 5-amino-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-8)-3,5-dideoxy-5-(propanoylamino)-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-8)-3,5-dideoxy-5-(propanoylamino)-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-9)-3,5-dideoxy-5-propanamido-D-glycero-D-galacto-non-2-ulosonic acid, ... (7 entities in total)
• Functional Keywords: antibody, fab, polysialic acid, complex, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 4
• Total formula weight: 100061.49

Authors

Beernink, P.T.,Agirre, J.,Beernink, B.P.,Moe, G.R. (deposition date: 2023-01-04, release date: 2026-03-18)

• Primary citation: Beernink, P.T.,Agirre, J.,Beernink, B.P.,Moe, G.R.; Structure of de-N-acetyl polysialic acid bound to an antibody Fab fragment; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.83 Å)