8FO0
The structure of a crystallizable variant of E. coli pyruvate formate-lyase activating enzyme bound to a partially cleaved SAM molecule
Summary for 8FO0
Entry DOI | 10.2210/pdb8fo0/pdb |
Descriptor | Pyruvate formate-lyase 1-activating enzyme, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ... (5 entities in total) |
Functional Keywords | radical sam, activase, pfl, oxidoreductase |
Biological source | Escherichia coli K-12 |
Total number of polymer chains | 1 |
Total formula weight | 29026.45 |
Authors | Moody, J.D.,Saxton, A.J.,Galambas, A.,Lawrence, C.M.,Broderick, J.B. (deposition date: 2022-12-29, release date: 2023-05-24, Last modification date: 2024-05-22) |
Primary citation | Moody, J.D.,Hill, S.,Lundahl, M.N.,Saxton, A.J.,Galambas, A.,Broderick, W.E.,Lawrence, C.M.,Broderick, J.B. Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage. J.Biol.Chem., 299:104791-104791, 2023 Cited by PubMed: 37156396DOI: 10.1016/j.jbc.2023.104791 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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