8FNZ
Acetylated tau repeat 1 and 2 fragment (AcR1R2)
Summary for 8FNZ
Entry DOI | 10.2210/pdb8fnz/pdb |
EMDB information | 28721 |
Descriptor | Microtubule-associated protein tau, acetylated repeat 1 and 2 fragment (1 entity in total) |
Functional Keywords | amyloid motif acetylation tau repeat domain post-translational modification, protein fibril |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 48 |
Total formula weight | 99520.90 |
Authors | Li, L.,Nguyen, A.B.,Mullapudi, V.,Joachimiak, L. (deposition date: 2022-12-29, release date: 2023-06-28, Last modification date: 2023-11-15) |
Primary citation | Li, L.,Nguyen, B.A.,Mullapudi, V.,Li, Y.,Saelices, L.,Joachimiak, L.A. Disease-associated patterns of acetylation stabilize tau fibril formation. Structure, 31:1025-1037.e4, 2023 Cited by PubMed: 37348495DOI: 10.1016/j.str.2023.05.020 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.88 Å) |
Structure validation
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