8FN8

Crystal structure of the C-terminal Fg domain of TNC with the single FN domain of PTPRZ

8FN8 の概要

• エントリーDOI: 10.2210/pdb8fn8/pdb
• 分子名称: Tenascin, Receptor-type tyrosine-protein phosphatase zeta, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: complex, receptor protein tyrosine phosphatase, extracellular matrix, fibronectin type iii, fibrinogen, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38337.66

構造登録者

Bouyain, S. (登録日: 2022-12-27, 公開日: 2023-07-12, 最終更新日: 2023-10-25)

• 主引用文献: Sinha, A.,Kawakami, J.,Cole, K.S.,Ladutska, A.,Nguyen, M.Y.,Zalmai, M.S.,Holder, B.L.,Broerman, V.M.,Matthews, R.T.,Bouyain, S.; Protein-protein interactions between tenascin-R and RPTP zeta /phosphacan are critical to maintain the architecture of perineuronal nets.; J.Biol.Chem., 299:104952-104952, 2023; PubMed: 37356715; DOI: 10.1016/j.jbc.2023.104952

実験手法

X-RAY DIFFRACTION (1.89 Å)