8FN1
CryoEM structure of Go-coupled NTSR1
Summary for 8FN1
Entry DOI | 10.2210/pdb8fn1/pdb |
EMDB information | 29303 |
Descriptor | Neurotensin/neuromedin N, Neurotensin receptor type 1, Guanine nucleotide-binding protein G(o) subunit alpha, ... (6 entities in total) |
Functional Keywords | gpcr, neurotensin receptor, allosterism, sbi-553, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 6 |
Total formula weight | 148060.42 |
Authors | Krumm, B.E.,DiBerto, J.F.,Olsen, R.H.J.,Kang, H.,Slocum, S.T.,Zhang, S.,Strachan, R.T.,Fay, J.F.,Roth, B.L. (deposition date: 2022-12-26, release date: 2023-03-29, Last modification date: 2023-04-19) |
Primary citation | Krumm, B.E.,DiBerto, J.F.,Olsen, R.H.J.,Kang, H.J.,Slocum, S.T.,Zhang, S.,Strachan, R.T.,Huang, X.P.,Slosky, L.M.,Pinkerton, A.B.,Barak, L.S.,Caron, M.G.,Kenakin, T.,Fay, J.F.,Roth, B.L. Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry, 62:1233-1248, 2023 Cited by PubMed: 36917754DOI: 10.1021/acs.biochem.3c00029 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.88 Å) |
Structure validation
Download full validation report