8FJM

Crystal Structure of the Trypanosoma brucei DOT1A histone H3K76 methyltransferase in complex with AdoHcy - P212121 space group

8FJM の概要

• エントリーDOI: 10.2210/pdb8fjm/pdb
• 分子名称: Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... (6 entities in total)
• 機能のキーワード: histone lysine methyltransferase, histone-modifying enzyme, dot1a, trypanosoma brucei, adohcy complex, transferase
• 由来する生物種: Trypanosoma brucei brucei TREU927
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 59690.36

構造登録者

Frisbie, V.S.,Hashimoto, H.,Debler, E.W. (登録日: 2022-12-20, 公開日: 2024-02-07)

• 主引用文献: Frisbie, V.S.,Hashimoto, H.,Xie, Y.,Baeza, J.,Nguyen, T.,Yuan, Z.,Garcia, B.A.,Debler, E.W.; Structure and Mechanism of the atypical Trypanosoma brucei DOT1A histone H3K76 methyltransferase; To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)