8FJC

Structure of the catalytic domain of Streptococcus mutans GtfB complexed to acarbose in tetragonal space group P4322

8FJC の概要

• エントリーDOI: 10.2210/pdb8fjc/pdb
• 関連するPDBエントリー: 8FG8 8FJ9
• 関連するBIRD辞書のPRD_ID: PRD_900007
• 分子名称: Glucosyltransferase-I, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CALCIUM ION, ... (6 entities in total)
• 機能のキーワード: gtfb, gtf-i, insoluble 1, 3-linked alpha glucans, biofilm, glucansucrase, inhibitor acarbose, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Streptococcus mutans
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 201788.09

構造登録者

Schormann, N.,Deivanayagam, C. (登録日: 2022-12-19, 公開日: 2023-05-17, 最終更新日: 2024-05-01)

• 主引用文献: Schormann, N.,Patel, M.,Thannickal, L.,Purushotham, S.,Wu, R.,Mieher, J.L.,Wu, H.,Deivanayagam, C.; The catalytic domains of Streptococcus mutans glucosyltransferases: a structural analysis.; Acta Crystallogr.,Sect.F, 79:119-127, 2023; PubMed: 37158310; DOI: 10.1107/S2053230X23003199

実験手法

X-RAY DIFFRACTION (2.5 Å)