8FH8

Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-003 Soaked In Hydrogen Peroxide

Summary for 8FH8

• Entry DOI: 10.2210/pdb8fh8/pdb
• Descriptor: Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {7-[(5-chloro-1,3-benzothiazol-2-yl)methyl]-8-oxo-7,8-dihydropyrazino[2,3-d]pyridazin-5-yl}acetic acid, ... (6 entities in total)
• Functional Keywords: complex, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37720.01

Authors

Arenas, R.,Wilson, D.K. (deposition date: 2022-12-13, release date: 2023-12-20)

• Primary citation: Arenas, R.,Wilson, D.K.; Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-003 Soaked In Hydrogen Peroxide; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)