8FF4

Cryo-EM structure of Cascade-DNA-TniQ-TnsC complex (composite) in type I-B CAST system

Summary for 8FF4

Entry DOI	10.2210/pdb8ff4/pdb
EMDB information	28980 28993 28994 28997 28998 29000 29001 29039 29040
Descriptor	Type I-B CRISPR-associated protein Cas5, TnsC, ADENOSINE-5'-TRIPHOSPHATE, ... (12 entities in total)
Functional Keywords	crispr, transposon, tnsc, tniq, dna binding protein
Biological source	Nostoc sp. 'Peltigera membranacea cyanobiont' 210A More
Total number of polymer chains	23
Total formula weight	807275.10
Authors	Chang, L.,Wang, S. (deposition date: 2022-12-07, release date: 2023-08-09, Last modification date: 2024-01-31)
Primary citation	Wang, S.,Gabel, C.,Siddique, R.,Klose, T.,Chang, L. Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector. Cell, 186:4204-4215.e19, 2023 Cited by PubMed: 37557170 DOI: 10.1016/j.cell.2023.07.010 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation