8FEG
CryoEM structure of Kappa Opioid Receptor bound to a semi-peptide and Gi1
Summary for 8FEG
Entry DOI | 10.2210/pdb8feg/pdb |
EMDB information | 29026 42601 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | gpcr, kappa opioid receptor, rosetta, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 150625.13 |
Authors | |
Primary citation | Muratspahic, E.,Deibler, K.,Han, J.,Tomasevic, N.,Jadhav, K.B.,Olive-Marti, A.L.,Hochrainer, N.,Hellinger, R.,Koehbach, J.,Fay, J.F.,Rahman, M.H.,Hegazy, L.,Craven, T.W.,Varga, B.R.,Bhardwaj, G.,Appourchaux, K.,Majumdar, S.,Muttenthaler, M.,Hosseinzadeh, P.,Craik, D.J.,Spetea, M.,Che, T.,Baker, D.,Gruber, C.W. Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor. Nat Commun, 14:8064-, 2023 Cited by PubMed: 38052802DOI: 10.1016/0006-2952(73)90196-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.54 Å) |
Structure validation
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