8FBZ
Crystal Structure of apo human Glutathione Synthetase Y270E
Summary for 8FBZ
Entry DOI | 10.2210/pdb8fbz/pdb |
Descriptor | Glutathione synthetase, SULFATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | glutathione synthesis atpase, biosynthetic protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 106052.14 |
Authors | Stanford, S.M.,Santelli, E.,Sankaran, B.,Murali, R.,Bottini, N. (deposition date: 2022-11-30, release date: 2024-05-08) |
Primary citation | Stanford, S.M.,Nguyen, T.P.,Chang, J.,Zhao, Z.,Hackman, G.L.,Santelli, E.,Sanders, C.M.,Katiki, M.,Dondossola, E.,Brauer, B.L.,Diaz, M.A.,Zhan, Y.,Ramsey, S.H.,Watson, P.A.,Sankaran, B.,Paindelli, C.,Parietti, V.,Mikos, A.G.,Lodi, A.,Bagrodia, A.,Elliott, A.,McKay, R.R.,Murali, R.,Tiziani, S.,Kettenbach, A.N.,Bottini, N. Targeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy. Sci Adv, 10:eadg7887-eadg7887, 2024 Cited by PubMed: 38295166DOI: 10.1126/sciadv.adg7887 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
Download full validation report