8FBZ

Crystal Structure of apo human Glutathione Synthetase Y270E

8FBZ の概要

• エントリーDOI: 10.2210/pdb8fbz/pdb
• 分子名称: Glutathione synthetase, SULFATE ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: glutathione synthesis atpase, biosynthetic protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 106052.14

構造登録者

Stanford, S.M.,Santelli, E.,Sankaran, B.,Murali, R.,Bottini, N. (登録日: 2022-11-30, 公開日: 2024-05-08)

• 主引用文献: Stanford, S.M.,Nguyen, T.P.,Chang, J.,Zhao, Z.,Hackman, G.L.,Santelli, E.,Sanders, C.M.,Katiki, M.,Dondossola, E.,Brauer, B.L.,Diaz, M.A.,Zhan, Y.,Ramsey, S.H.,Watson, P.A.,Sankaran, B.,Paindelli, C.,Parietti, V.,Mikos, A.G.,Lodi, A.,Bagrodia, A.,Elliott, A.,McKay, R.R.,Murali, R.,Tiziani, S.,Kettenbach, A.N.,Bottini, N.; Targeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy.; Sci Adv, 10:eadg7887-eadg7887, 2024; PubMed: 38295166; DOI: 10.1126/sciadv.adg7887

実験手法

X-RAY DIFFRACTION (1.59 Å)