8FA1

Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with N969K mutation

Summary for 8FA1

Entry DOI	10.2210/pdb8fa1/pdb
EMDB information	28947
Descriptor	Ferritin, Dps family protein and Spike protein S2' chimera, Spike protein S2' HR2 (2 entities in total)
Functional Keywords	spike, hr1hr2, fusion, scaffold, viral protein
Biological source	Nostoc punctiforme PCC 73102 More
Total number of polymer chains	6
Total formula weight	101128.72
Authors	Yang, K.,Brunger, A.T. (deposition date: 2022-11-25, release date: 2023-03-29, Last modification date: 2023-04-05)
Primary citation	Yang, K.,Wang, C.,Kreutzberger, A.J.B.,White, K.I.,Pfuetzner, R.A.,Esquivies, L.,Kirchhausen, T.,Brunger, A.T. Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor. Proc.Natl.Acad.Sci.USA, 120:e2300360120-e2300360120, 2023 Cited by PubMed: 36940324 DOI: 10.1073/pnas.2300360120 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.51 Å)

Structure validation