8F6L
anti-BTLA monoclonal antibody h25F7 in complex with BTLA
Summary for 8F6L
Entry DOI | 10.2210/pdb8f6l/pdb |
Related | 8F60 |
Descriptor | h25F7 Fab heavy chain, h25F7 Fab light chain, B- and T-lymphocyte attenuator, ... (4 entities in total) |
Functional Keywords | monoclonal antibody, complex, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 63694.84 |
Authors | Hendle, J.,Atwell, S.,Lieu, R.,Hickey, M.,Weichert, K. (deposition date: 2022-11-16, release date: 2023-05-24, Last modification date: 2023-10-25) |
Primary citation | Cheung, T.C.,Atwell, S.,Bafetti, L.,Cuenca, P.D.,Froning, K.,Hendle, J.,Hickey, M.,Ho, C.,Huang, J.,Lieu, R.,Lim, S.,Lippner, D.,Obungu, V.,Ward-Kavanagh, L.,Weichert, K.,Ware, C.F.,Vendel, A.C. Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA. Structure, 31:958-, 2023 Cited by PubMed: 37279757DOI: 10.1016/j.str.2023.05.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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