8F5X

Crystal structure of human eosinophil-derived neurotoxin (EDN, ribonuclease 2) in complex with 5'-adenosine monophosphate (AMP)

8F5X の概要

• エントリーDOI: 10.2210/pdb8f5x/pdb
• 分子名称: Non-secretory ribonuclease, SUCCINIC ACID, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: edn, rnase 2, ribonuclease, eosinophil-derived neurotoxin, transphosphorylase, amp, adenosine monophosphate, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16561.51

構造登録者

Tran, T.T.Q.,Pham, N.T.H.,Calmettes, C.,Doucet, N. (登録日: 2022-11-15, 公開日: 2023-11-29, 最終更新日: 2024-05-29)

• 主引用文献: Tran, T.T.Q.,Narayanan, C.,Loes, A.N.,Click, T.H.,Pham, N.T.H.,Letourneau, M.,Harms, M.J.,Calmettes, C.,Agarwal, P.K.,Doucet, N.; Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases.; J.Biol.Chem., 300:107280-107280, 2024; PubMed: 38588810; DOI: 10.1016/j.jbc.2024.107280

実験手法

X-RAY DIFFRACTION (1.7 Å)