8F25

Cryo-EM structure of Lumazine synthase nanoparticle linked to VP8* antigen

Summary for 8F25

• Entry DOI: 10.2210/pdb8f25/pdb
• EMDB information: 28807
• Descriptor: 6,7-dimethyl-8-ribityllumazine synthase (1 entity in total)
• Functional Keywords: rotavirus, vp8*, lumazine synthase, nanoparticle, viral protein
• Biological source: Aquifex aeolicus
• Total number of polymer chains: 60
• Total formula weight: 1003691.16

Authors

Mangala Prasad, V.,Lee, K.K. (deposition date: 2022-11-07, release date: 2023-04-12, Last modification date: 2024-01-10)

• Primary citation: Roier, S.,Mangala Prasad, V.,McNeal, M.M.,Lee, K.K.,Petsch, B.,Rauch, S.; mRNA-based VP8* nanoparticle vaccines against rotavirus are highly immunogenic in rodents.; Npj Vaccines, 8:190-190, 2023; PubMed: 38129390; DOI: 10.1038/s41541-023-00790-z

Experimental method

ELECTRON MICROSCOPY (2.6 Å)