8F1Z

EGFR kinase in complex with Bayer #33

Summary for 8F1Z

• Entry DOI: 10.2210/pdb8f1z/pdb
• Descriptor: Epidermal growth factor receptor, (2P)-3-(3-chloro-2-methoxyanilino)-2-[3-(2-methoxy-2-methylpropoxy)pyridin-4-yl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, CITRIC ACID, ... (4 entities in total)
• Functional Keywords: egfr, kinase, inhibitor, exon 20, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 38491.64

Authors

Beyett, T.S.,Eck, M.J. (deposition date: 2022-11-06, release date: 2023-11-08)

• Primary citation: Beyett, T.S.,Eck, M.J.; EGFR kinase in complex with Bayer #33; To be published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)