8EZ6

The DBC1/SIRT1 Interaction is Choreographed by Post-translational Modification

8EZ6 の概要

• エントリーDOI: 10.2210/pdb8ez6/pdb
• 分子名称: Cell cycle and apoptosis regulator protein 2 (2 entities in total)
• 機能のキーワード: dbc1, s1-like, insulin signaling, liver metabolism, chaperone, gene regulation
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 16000.15

構造登録者

Krzysiak, T.C.,Gronenborn, A.M. (登録日: 2022-10-31, 公開日: 2024-03-27, 最終更新日: 2024-04-17)

• 主引用文献: Krzysiak, T.C.,Choi, Y.J.,Kim, Y.J.,Yang, Y.,DeHaven, C.,Thompson, L.,Ponticelli, R.,Mermigos, M.M.,Thomas, L.,Marquez, A.,Sipula, I.,Kemper, J.K.,Jurczak, M.,Thomas, G.,Gronenborn, A.M.; Inhibitory protein-protein interactions of the SIRT1 deacetylase are choreographed by post-translational modification.; Protein Sci., 33:e4938-e4938, 2024; PubMed: 38533551; DOI: 10.1002/pro.4938

実験手法

X-RAY DIFFRACTION (2 Å)