8EXQ
Cryo-EM structure of S. aureus BlaR1 with C1 symmetry
Summary for 8EXQ
Entry DOI | 10.2210/pdb8exq/pdb |
EMDB information | 28658 28659 28660 28661 28662 |
Descriptor | Beta-lactam sensor/signal transducer BlaR1, ZINC ION (2 entities in total) |
Functional Keywords | antibiotic resistance, beta-lactam antibiotics, mrsa, blar1, mecr1, cryo-em, transmembrane signalling, signaling protein |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 2 |
Total formula weight | 142670.22 |
Authors | Worrall, L.J.,Alexander, J.A.N.,Vuckovic, M.,Strynadka, N.C.J. (deposition date: 2022-10-25, release date: 2023-01-11, Last modification date: 2024-06-19) |
Primary citation | Alexander, J.A.N.,Worrall, L.J.,Hu, J.,Vuckovic, M.,Satishkumar, N.,Poon, R.,Sobhanifar, S.,Rosell, F.I.,Jenkins, J.,Chiang, D.,Mosimann, W.A.,Chambers, H.F.,Paetzel, M.,Chatterjee, S.S.,Strynadka, N.C.J. Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus. Nature, 613:375-382, 2023 Cited by PubMed: 36599987DOI: 10.1038/s41586-022-05583-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.9 Å) |
Structure validation
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